SCHEMBL8632609

SCHEMBL8632609

[O]c1ccc(S(=O)(=O)c2ccc([O])cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
HTR6 P50406 4/20 0.55
GAA P10253 3/20 0.55
CYP3A4 P08684 2/20 0.55
MAPK1 P28482 2/20 0.55
TSHR P16473 2/20 0.55
LMNA P02545 1/20 0.55
MPO P05164 1/20 0.55
CYP2C9 P11712 1/20 0.55
PKM P14618 4/20 0.48
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 3/20 0.41
POLB P06746 2/20 0.41
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9215643 0.89 HTR6 (0.74) ALDH1A1HTR6GAACYP3A4MAPK1
SCHEMBL2038611 0.87 GAA (0.57) ALDH1A1HTR6GAACYP3A4MAPK1
SCHEMBL4392274 0.87 GAA (0.80) ALDH1A1GAACYP3A4CYP2C9PKM
SCHEMBL3781114 0.84 ALDH1A1 (0.42) ALDH1A1HTR6GAACYP3A4MAPK1
(Phenylsulfonyl)Benzene SCHEMBL27515700 0.75 HTR6 (0.62) ALDH1A1HTR6CYP3A4TSHRLMNA
SCHEMBL1805283 0.75 CA2 (0.65) ALDH1A1TSHRMAPT
SCHEMBL1203157 0.75 LMNA (0.62) ALDH1A1TSHRLMNACYP2C9MEN1
SCHEMBL8696138 0.75 TSHR (0.48) ALDH1A1HTR6GAACYP3A4MAPK1
SCHEMBL517832 0.75 ENPP2 (0.59)
SCHEMBL5051390 0.73 HTR6 (0.93) ALDH1A1HTR6GAACYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4426512-A THIO- OR SULFONYL BIS((P-PHENYLENEOXY)ACETIC ACID) EASTMAN KODAK COMPANY (US) 1984-01-17 US claimed
EP-0606955-B1 Image formation in color reversal materials using weak and strong inhibitors EASTMAN KODAK CO (US) 1998-07-08 EP disclosed
EP-0606953-B1 Image formation in color reversal materials using strong inhibitors EASTMAN KODAK CO (US) 1997-05-21 EP disclosed
EP-0608029-B1 Dir couplers with hydrolyzable inhibitors for use in high PH processed films EASTMAN KODAK CO (US) 1997-03-26 EP disclosed
US-5411839-A Light sensitive elements for color photography EASTMAN KODAK COMPANY (US) 1995-05-02 US disclosed
US-5399465-A Photography, standard development EASTMAN KODAK COMPANY (US) 1995-03-21 US disclosed
US-5399466-A [Method of processing] photographic elements having fogged grains and development inhibitors for interimage EASTMAN KODAK COMPANY (US) 1995-03-21 US disclosed
US-5380633-A A support with developers for photographic silver halide emulsions EASTMAN KODAK COMPANY (US) 1995-01-10 US disclosed
EP-0608029-A2 Dir couplers with hydrolyzable inhibitors for use in high PH processed films EASTMAN KODAK COMPANY (US) 1994-07-27 EP disclosed
EP-0606952-A2 Color photographic reversal element with improved color reproduction EASTMAN KODAK COMPANY (US) 1994-07-20 EP disclosed
EP-0606954-A2 Reversal elements with selected development inhibitors and absorber dyes EASTMAN KODAK COMPANY (US) 1994-07-20 EP disclosed
EP-0606953-A2 Image formation in color reversal materials using strong inhibitors EASTMAN KODAK COMPANY (US) 1994-07-20 EP disclosed
EP-0606955-A2 Image formation in color reversal materials using weak and strong inhibitors EASTMAN KODAK COMPANY (US) 1994-07-20 EP disclosed
EP-0606951-A2 Photographic elements having fogged grains and development inhibitors for interimage EASTMAN KODAK COMPANY (US) 1994-07-20 EP disclosed
US-5310642-A Specific decomposiiton half-life EASTMAN KODAK COMPANY (US) 1994-05-10 US disclosed