Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 8/20 | 0.40 |
| ▸ | NPC1 | O15118 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 3/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | GYS1 | P13807 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216188 | 0.88 | RAB9A (0.36) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL9215456 | 0.85 | TTR (0.38) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL9221437 | 0.85 | AHR (0.34) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL9213356 | 0.84 | RAB9A (0.36) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL9215736 | 0.82 | TSHR (0.38) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL9218452 | 0.82 | MEN1 (0.40) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL9218594 | 0.81 | RAB9A (0.40) | KMORAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL9168959 | 0.81 | RAB9A (0.38) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL8992830 | 0.81 | RAB9A (0.38) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL9215756 | 0.80 | SRC (0.45) | RAB9ANPC1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269859-B2 | Pyrazolotriazine compounds | OTSUKA PHARMA CO LTD (JP) | 1995-10-18 | — | — | EP | disclosed |
| US-4824834-A | TREATING GOUT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-04-25 | — | — | US | disclosed |
| EP-0269859-A2 | Pyrazolotriazine compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-08 | — | — | EP | disclosed |