Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993124 | 0.87 | GPR119 (0.37) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL8992897 | 0.84 | FYN (0.41) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL8992955 | 0.83 | NPC1 (0.43) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL9215740 | 0.81 | KMO (0.41) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL9221282 | 0.80 | GPR119 (0.37) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL8993403 | 0.79 | RAB9A (0.44) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL8993290 | 0.78 | GPR119 (0.41) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL9168959 | 0.78 | RAB9A (0.38) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL8992904 | 0.78 | GPR119 (0.39) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL9216188 | 0.77 | RAB9A (0.36) | RAB9ANPC1MEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |