Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220203 | 0.90 | RAB9A (0.34) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL9210159 | 0.86 | RAB9A (0.34) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL9216083 | 0.85 | ALDH1A1 (0.36) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL9215740 | 0.84 | KMO (0.41) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL9168959 | 0.84 | RAB9A (0.38) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL9216515 | 0.83 | RAB9A (0.34) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL9215050 | 0.83 | MAPT (0.43) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL9216188 | 0.81 | RAB9A (0.36) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL9215802 | 0.79 | RAB9A (0.38) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL9215456 | 0.79 | TTR (0.38) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269859-B2 | Pyrazolotriazine compounds | OTSUKA PHARMA CO LTD (JP) | 1995-10-18 | — | — | EP | disclosed |
| US-4824834-A | TREATING GOUT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-04-25 | — | — | US | disclosed |