Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213423 | 0.99 | ADRA1B (0.42) | ADRA1BACHEMEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL9216007 | 0.96 | MEN1 (0.45) | ADRA1BMEN1KMT2AGAAABCB1 | |
| Hydrochloric Acid SCHEMBL9216051 | 0.93 | HTR1A (0.44) | ADRA1BMEN1KMT2AABCB1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9204461 | 0.92 | GAA (0.48) | ADRA1BMEN1KMT2AGAAABCB1 | |
| Hydrochloric Acid SCHEMBL9206715 | 0.89 | ADRA1B (0.47) | ADRA1BMEN1KMT2AGAASIGMAR1 | |
| SCHEMBL9215919 | 0.89 | KDM2B (0.41) | ADRA1BACHEABCB1 | |
| SCHEMBL9213761 | 0.89 | CHRNB2 (0.43) | ADRA1BABCB1 | |
| Hydrochloric Acid SCHEMBL9214061 | 0.88 | MEN1 (0.46) | MEN1KMT2AGAAABCB1 | |
| SCHEMBL9212953 | 0.88 | MEN1 (0.41) | ACHEMEN1KMT2AGAASIGMAR1 | |
| SCHEMBL9204619 | 0.88 | KDM2B (0.42) | ADRA1BACHEMEN1KMT2AABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |