Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204195 | 0.71 | SMN1; SMN2 (0.47) | MAPK1GAANPSR1MAPTHTR1E | |
| SCHEMBL9678880 | 0.70 | ALDH1A1 (0.40) | MAPK1GAANPSR1MAPTHTR1E | |
| SCHEMBL9216138 | 0.68 | ALDH1A1 (0.43) | NPSR1MAPTHTR1ES1PR3MEN1 | |
| SCHEMBL12436884 | 0.68 | HSD17B10 (0.47) | MAPK1NPSR1MAPTHTR1ES1PR3 | |
| SCHEMBL22230818 | 0.68 | NPSR1 (0.46) | MAPK1GAANPSR1MAPTHTR1E | |
| SCHEMBL6607473 | 0.65 | NPSR1 (0.52) | MAPK1NPSR1MAPTHTR1ES1PR3 | |
| SCHEMBL9208754 | 0.65 | ALDH1A1 (0.49) | MAPK1GAANPSR1MAPTHTR1E | |
| SCHEMBL2103568 | 0.65 | MAPK1 (0.55) | MAPK1GAAMAPTMEN1KMT2A | |
| Acetic Acid SCHEMBL27877969 | 0.64 | MAPK1 (0.71) | MAPK1MEN1KMT2ALMNATSHR | |
| Acetic Acid SCHEMBL27904062 | 0.62 | MAPK1 (0.68) | MAPK1MEN1KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995004053-A1 | UREA AND THIOUREA DERIVATIVES AND PROCESS FOR THEIR PREPARATION | PHARMACIA S.P.A. (IT) | 1995-02-09 | — | — | WO | disclosed |