Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTR1E | P28566 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204195 | 0.72 | SMN1; SMN2 (0.47) | ALDH1A1MAPTNPSR1HTR1ES1PR3 | |
| SCHEMBL1718880 | 0.69 | CSNK2A2 (0.45) | ALDH1A1CSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL12436884 | 0.69 | HSD17B10 (0.47) | ALDH1A1MAPTNPSR1HTR1ES1PR3 | |
| SCHEMBL9208754 | 0.68 | ALDH1A1 (0.49) | ALDH1A1MAPTNPSR1HTR1ES1PR3 | |
| SCHEMBL9216133 | 0.68 | MAPK1 (0.41) | ALDH1A1MAPTNPSR1HTR1ES1PR3 | |
| SCHEMBL9678880 | 0.68 | ALDH1A1 (0.40) | ALDH1A1MAPTNPSR1HTR1ES1PR3 | |
| SCHEMBL1706183 | 0.67 | KMT2A (0.65) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL11068118 | 0.64 | ALDH1A1 (0.72) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL17109521 | 0.64 | MEN1 (0.47) | ALDH1A1MAPTNPSR1HTR1ES1PR3 | |
| SCHEMBL9219371 | 0.64 | LOXL2 (0.46) | ALDH1A1MAPTNPSR1HTR1ES1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995004053-A1 | UREA AND THIOUREA DERIVATIVES AND PROCESS FOR THEIR PREPARATION | PHARMACIA S.P.A. (IT) | 1995-02-09 | — | — | WO | disclosed |