SCHEMBL921620

SCHEMBL921620

CC(C)Cc1cccc(Oc2ccc(CNC(=O)c3cccnc3N)cc2)c1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 1/20 0.52
HPGD P15428 3/20 0.48
KMT2A Q03164 2/20 0.48
PPARG P37231 2/20 0.47
PPARA Q07869 2/20 0.47
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 1/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
KDM4E B2RXH2 1/20 0.46
USP2 O75604 1/20 0.46
PPARD Q03181 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920053 0.92 MAPK8 (0.52) MAPK8HPGDKMT2APPARGPPARA
SCHEMBL920001 0.92 PPARG (0.49) MAPK8HPGDKMT2APPARGPPARA
SCHEMBL920396 0.90 MAPK8 (0.50) MAPK8HPGDKMT2AALDH1A1MEN1
SCHEMBL919798 0.89 MAPK8 (0.55) MAPK8HPGDKMT2AALDH1A1MEN1
SCHEMBL920431 0.88 HPGD (0.51) MAPK8HPGDKMT2APPARGPPARA
SCHEMBL919305 0.87 MAPK8 (0.53) MAPK8HPGDKMT2AALDH1A1MEN1
SCHEMBL919967 0.87 MAPK8 (0.50) MAPK8HPGDKMT2AALDH1A1MEN1
SCHEMBL921735 0.87 KMT2A (0.52) MAPK8HPGDKMT2APPARGPPARA
SCHEMBL920586 0.87 KMT2A (0.52) MAPK8HPGDKMT2APPARGPPARA
SCHEMBL920562 0.87 HPGD (0.56) MAPK8HPGDKMT2APPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAPK8 2313/4885HPGD 1273/4885KMT2A 2469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.