SCHEMBL920562

SCHEMBL920562

CCc1ccc(Oc2cccc(CNC(=O)c3cccnc3N)c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.56
KMT2A Q03164 2/20 0.56
MAPK8 P45983 1/20 0.52
ALDH1A1 P00352 2/20 0.51
KDM4E B2RXH2 1/20 0.51
USP2 O75604 1/20 0.51
LMNA P02545 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47
MMP13 P45452 1/20 0.47
MEN1 O00255 1/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
MAPK14 Q16539 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919798 0.96 MAPK8 (0.55) HPGDKMT2AMAPK8ALDH1A1KDM4E
SCHEMBL920646 0.95 HPGD (0.59) HPGDKMT2AMAPK8ALDH1A1KDM4E
SCHEMBL922632 0.92 HPGD (0.54) HPGDKMT2AMAPK8ALDH1A1KDM4E
SCHEMBL919694 0.92 HPGD (0.61) HPGDKMT2AMAPK8ALDH1A1KDM4E
SCHEMBL920473 0.91 HPGD (0.57) HPGDKMT2AMAPK8ALDH1A1LMNA
SCHEMBL920077 0.91 HPGD (0.62) HPGDKMT2AMAPK8ALDH1A1KDM4E
SCHEMBL921092 0.91 MMP13 (0.58) HPGDKMT2AMAPK8ALDH1A1KDM4E
SCHEMBL1680406 0.90 MAPK8 (0.63) HPGDKMT2AMAPK8ALDH1A1KDM4E
SCHEMBL920783 0.90 HPGD (0.54) HPGDKMT2AMAPK8ALDH1A1KDM4E
SCHEMBL921759 0.90 HPGD (0.54) HPGDKMT2AMAPK8ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885KMT2A 2469/4885MAPK8 2313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.