Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27438850 | 0.89 | CA1 (0.58) | PTPN1MAPTCA1CA2KMT2A | |
| SCHEMBL3610930 | 0.86 | PTPN1 (0.59) | PTPN1MAPTCA1CA2NPC1 | |
| SCHEMBL11901558 | 0.83 | MAPT (0.57) | PTPN1MAPTCA1CA2NPC1 | |
| SCHEMBL974921 | 0.80 | PTPN1 (0.54) | PTPN1MAPTCA1CA2NPC1 | |
| SCHEMBL27947376 | 0.79 | MAPT (0.54) | PTPN1MAPTCA1CA2NPC1 | |
| SCHEMBL9218345 | 0.79 | CA1 (0.56) | PTPN1MAPTCA1CA2NPC1 | |
| SCHEMBL1490754 | 0.77 | KDM4E (0.49) | PTPN1MAPTCA1CA2NPC1 | |
| SCHEMBL11672606 | 0.76 | PTPN1 (0.89) | PTPN1MAPTNPC1KMT2ARAB9A | |
| SCHEMBL9219744 | 0.76 | PTPN1 (0.56) | PTPN1MAPTNPC1KMT2ARAB9A | |
| SCHEMBL28291736 | 0.76 | CA1 (0.62) | PTPN1MAPTCA1CA2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |