Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3610930 | 0.89 | PTPN1 (0.59) | PTPN1MAPTNPC1TP53LMNA | |
| SCHEMBL9218345 | 0.84 | CA1 (0.56) | PTPN1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9212323 | 0.84 | L3MBTL1 (0.51) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9217844 | 0.84 | L3MBTL1 (0.49) | PTPN1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8201626 | 0.83 | L3MBTL1 (0.60) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL11745212 | 0.83 | L3MBTL1 (0.47) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9220492 | 0.80 | MCL1 (0.65) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL11901558 | 0.79 | MAPT (0.57) | PTPN1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9219884 | 0.78 | MCL1 (0.46) | PTPN1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL29591307 | 0.78 | CA1 (0.61) | PTPN1MAPTSMN1; SMN2TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |