Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 9/20 | 0.43 |
| ▸ | HTR2C | P28335 | 7/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207494 | 0.79 | PARP1 (0.48) | EEDHTR2AHTR2CHTR2BEHMT2 | |
| SCHEMBL9216049 | 0.74 | MEN1 (0.48) | HTR2AHTR2CHTR2BACHE | |
| SCHEMBL9212186 | 0.74 | SMN1; SMN2 (0.48) | EEDHTR2AHTR2CHTR2BEHMT2 | |
| SCHEMBL4813403 | 0.74 | ABCB1 (0.52) | ACHEABCB1 | |
| SCHEMBL31134797 | 0.73 | ABCB1 (0.55) | ACHEABCB1 | |
| Hydrochloric Acid SCHEMBL1625012 | 0.73 | ABCB1 (0.51) | ACHEABCB1 | |
| SCHEMBL3721098 | 0.72 | SMN1; SMN2 (0.57) | ABCB1 | |
| SCHEMBL1777570 | 0.72 | DRD2 (0.55) | HTR2AHTR2C | |
| SCHEMBL9208378 | 0.71 | MEN1 (0.47) | HTR2AHTR2CHTR2BACHE | |
| SCHEMBL9204902 | 0.71 | SMN1; SMN2 (0.47) | HTR2CHTR2BEHMT2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0292840-A2 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |