Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GART | P22102 | 8/20 | 0.45 |
| ▸ | ATIC | P31939 | 3/20 | 0.40 |
| ▸ | FNTA | P49354 | 3/20 | 0.39 |
| ▸ | FNTB | P49356 | 3/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216949 | 1.00 | GART (0.45) | GARTATICFNTAFNTBPGGT1B | |
| SCHEMBL9211571 | 0.92 | GART (0.52) | GARTATICTYMSSOST | |
| SCHEMBL10570448 | 0.92 | GART (0.52) | GARTATICTYMSSOST | |
| SCHEMBL10574300 | 0.88 | GART (0.44) | GARTATICTYMSSOST | |
| SCHEMBL10574310 | 0.88 | GART (0.44) | GARTATICTYMSSOST | |
| SCHEMBL10567798 | 0.88 | GART (0.42) | GARTATICTYMS | |
| SCHEMBL10567793 | 0.88 | GART (0.42) | GARTATICTYMS | |
| SCHEMBL8820727 | 0.82 | GART (0.52) | GARTATIC | |
| SCHEMBL8820737 | 0.82 | GART (0.52) | GARTATIC | |
| SCHEMBL9525469 | 0.80 | GART (0.41) | GARTFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344922-B1 | N-(N-(tetrahydropyrido(2,3-d)pyrimidinylmethyl)-aminomethylbenzoyl)glutamic acid derivatives | UNIV PRINCETON (US) | 1995-10-18 | — | — | EP | disclosed |
| EP-0344922-A2 | N-(N-(tetrahydropyrido(2,3-d)pyrimidinylmethyl)-aminomethylbenzoyl)glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-12-06 | — | — | EP | disclosed |
| US-4871746-A | N-[N-(tetrahydropyrido[2,3-D]pyrimidinylmethyl)-aminomethylbenzoyl]glutamic acid derivatives as neoplastic growth inhibitors | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-10-03 | — | — | US | disclosed |