Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9212120 | 0.88 | DRD4 (0.42) | DRD4DRD3HTR1AADRA1BMEN1 | |
| SCHEMBL9214421 | 0.84 | HRH3 (0.40) | MEN1KMT2AHRH3 | |
| Hydrochloric Acid SCHEMBL9206844 | 0.84 | CYP3A4 (0.47) | DRD4DRD3HTR1AADRA1BMEN1 | |
| SCHEMBL9213338 | 0.83 | PDE4B (0.56) | DRD4DRD3PDE4B | |
| Hydrochloric Acid SCHEMBL9208307 | 0.83 | HRH3 (0.39) | MEN1KMT2AHRH3 | |
| Hydrochloric Acid SCHEMBL9208281 | 0.82 | HTR1A (0.43) | DRD4DRD3HTR1AADRA1BMEN1 | |
| Hydrochloric Acid SCHEMBL9215824 | 0.81 | MEN1 (0.42) | DRD4DRD3HTR1AADRA1BMEN1 | |
| SCHEMBL9215931 | 0.80 | HRH3 (0.38) | HRH3 | |
| SCHEMBL9205342 | 0.79 | KDM4E (0.38) | DRD3HTR1AHRH3 | |
| Hydrochloric Acid SCHEMBL9213450 | 0.79 | ADRA1B (0.43) | DRD4DRD3HTR1AADRA1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |