Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9431056 | 0.93 | MAPT (0.53) | MAPTATML3MBTL1MAOBKCNH2 | |
| SCHEMBL9212323 | 0.86 | L3MBTL1 (0.51) | MAPTATML3MBTL1MAOBKCNH2 | |
| SCHEMBL9210201 | 0.81 | MCL1 (0.57) | MAPTATML3MBTL1MAOBKCNH2 | |
| SCHEMBL9217469 | 0.81 | KDM4E (0.54) | MAPTATML3MBTL1MAOBKCNH2 | |
| SCHEMBL19661814 | 0.81 | KCNH2 (0.60) | MAPTL3MBTL1KCNH2NPC1TP53 | |
| SCHEMBL8201626 | 0.79 | L3MBTL1 (0.60) | MAPTATML3MBTL1KCNH2NPC1 | |
| SCHEMBL9220492 | 0.78 | MCL1 (0.65) | MAPTMAOBKCNH2NPC1CSNK2A2 | |
| SCHEMBL9221054 | 0.78 | MAPT (0.54) | MAPTATML3MBTL1MAOBKCNH2 | |
| SCHEMBL9209323 | 0.78 | L3MBTL1 (0.47) | MAPTATML3MBTL1MAOBKCNH2 | |
| SCHEMBL9430174 | 0.78 | KDM4E (0.59) | MAPTATMMAOBKCNH2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |