SCHEMBL9217601

SCHEMBL9217601

O=Cc1cnn(-c2c(Cl)cc(OC(F)(F)F)cc2Cl)n1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
RECQL P46063 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
NPBWR1 P48145 2/20 0.31
MCHR1 Q99705 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9213953 0.82 GABRB3 (0.43)
SCHEMBL9215564 0.79 MAPK1 (0.36) MAPK1L3MBTL1
SCHEMBL9218013 0.77 NMT1 (0.33)
SCHEMBL9500764 0.74 GAA (0.38) MAPT
SCHEMBL9208552 0.70 NPC1 (0.47) MAPTRECQLL3MBTL1
SCHEMBL9212684 0.69 GABRB3 (0.40)
SCHEMBL9717689 0.69 GABRB3 (0.40)
SCHEMBL1039808 0.69 MEN1 (0.40)
SCHEMBL9211834 0.67 ERN1 (0.34)
SCHEMBL9768126 0.66 GABRB3 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0412849-B1 Azole pesticides AGREVO UK LTD (GB) 1995-12-20 EP disclosed
US-5189053-A Insecticide, acaricide and endoparasiticide SCHERING AGROCHEMICALS LIMITED (GB) 1993-02-23 US disclosed
US-5109012-A 2-IMIDAZOL(IN)E SUBSTITUTED ARYL-1,2,3-TRIAZOLE PESTICIDES SCHERING AGROCHEMICALS LIMITED (GB) 1992-04-28 US disclosed
EP-0412849-A2 Azole pesticides AgrEvo UK Limited (GB) 1991-02-13 EP disclosed