SCHEMBL9215564

SCHEMBL9215564

O=Cc1cnn(-c2c(Cl)cc(Cl)cc2Cl)n1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.36
ERN1 O75460 1/20 0.34
TERT O14746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
CDK4 P11802 1/20 0.32
CCND1 P24385 1/20 0.32
MEN1 O00255 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KDR P35968 1/20 0.32
S1PR4 O95977 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9218013 0.87 NMT1 (0.33)
SCHEMBL9213953 0.83 GABRB3 (0.43) KMT2A
SCHEMBL9217601 0.79 MAPT (0.32) MAPK1L3MBTL1
SCHEMBL11691729 0.74 P2RX7 (0.42) TERTMEN1KMT2ASMN1; SMN2
SCHEMBL5487008 0.73 PKM (0.43) TERTMEN1KMT2ASMN1; SMN2
SCHEMBL9208552 0.70 NPC1 (0.47) L3MBTL1MEN1KMT2ASMN1; SMN2NPSR1
SCHEMBL9717689 0.69 GABRB3 (0.40) KMT2A
SCHEMBL9212684 0.69 GABRB3 (0.40) KMT2A
SCHEMBL9501932 0.68 GAA (0.46) MEN1KMT2A
SCHEMBL9218040 0.68 GAA (0.46) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0412849-B1 Azole pesticides AGREVO UK LTD (GB) 1995-12-20 EP disclosed
US-5189053-A Insecticide, acaricide and endoparasiticide SCHERING AGROCHEMICALS LIMITED (GB) 1993-02-23 US disclosed
US-5109012-A 2-IMIDAZOL(IN)E SUBSTITUTED ARYL-1,2,3-TRIAZOLE PESTICIDES SCHERING AGROCHEMICALS LIMITED (GB) 1992-04-28 US disclosed
EP-0412849-A2 Azole pesticides AgrEvo UK Limited (GB) 1991-02-13 EP disclosed