Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213953 | 0.85 | GABRB3 (0.43) | NPC1RAB9AKMT2ALMNA | |
| SCHEMBL15639626 | 0.79 | POLB (0.49) | NPC1RAB9APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9500826 | 0.74 | ALDH1A1 (0.39) | NPC1RAB9APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9217450 | 0.74 | ALDH1A1 (0.39) | NPC1RAB9APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9768243 | 0.73 | KMT2A (0.46) | NPC1RAB9APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9212684 | 0.72 | GABRB3 (0.40) | NPC1RAB9AKMT2ALMNA | |
| SCHEMBL9717689 | 0.72 | GABRB3 (0.40) | NPC1RAB9AKMT2ALMNA | |
| SCHEMBL23367252 | 0.71 | P2RX7 (0.40) | KDM4EMAPTNPSR1ATM | |
| SCHEMBL9217601 | 0.70 | MAPT (0.32) | MAPTRECQLL3MBTL1 | |
| SCHEMBL9215564 | 0.70 | MAPK1 (0.36) | SMN1; SMN2MEN1KMT2ANPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412849-B1 | Azole pesticides | AGREVO UK LTD (GB) | 1995-12-20 | — | — | EP | disclosed |
| US-5189053-A | Insecticide, acaricide and endoparasiticide | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-02-23 | — | — | US | disclosed |
| US-5109012-A | 2-IMIDAZOL(IN)E SUBSTITUTED ARYL-1,2,3-TRIAZOLE PESTICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-04-28 | — | — | US | disclosed |
| CN-1049341-A | AZOLE PESTICIDES | SCHERING AGROCHEMICALS LTD (GB) | 1991-02-20 | — | — | CN | disclosed |