Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212883 | 0.86 | PTGDR2 (0.57) | PTGDR2MAPT | |
| SCHEMBL9214962 | 0.86 | PTGDR2 (0.57) | PTGDR2MAPT | |
| SCHEMBL14419539 | 0.84 | PTGDR2 (0.69) | PTGDR2MAPTPPARD | |
| SCHEMBL14066214 | 0.82 | PTGDR2 (0.60) | PTGDR2 | |
| SCHEMBL21987043 | 0.82 | PTGDR2 (0.80) | PTGDR2 | |
| SCHEMBL21987061 | 0.82 | PTGDR2 (1.00) | PTGDR2MAPTMAPK1 | |
| SCHEMBL9214221 | 0.81 | TDP1 (0.58) | PTGDR2MAPT | |
| SCHEMBL21987094 | 0.79 | PTGDR2 (0.74) | PTGDR2NPC1MAPT | |
| SCHEMBL29951797 | 0.78 | PTGDR2 (0.69) | PTGDR2MAPTHTT | |
| SCHEMBL7067039 | 0.77 | PTGDR2 (0.50) | PTGDR2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |