Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217624 | 0.86 | PTGDR2 (0.69) | PTGDR2MAPT | |
| SCHEMBL9214962 | 0.86 | PTGDR2 (0.57) | PTGDR2MAPTTP53KDM4E | |
| SCHEMBL14419297 | 0.84 | PTGDR2 (0.57) | PTGDR2PKMMAPTTP53SMN1; SMN2 | |
| SCHEMBL30785080 | 0.84 | MAPT (0.46) | PTGDR2MEN1MAPTKMT2ARECQL | |
| SCHEMBL3925716 | 0.83 | MAPT (0.61) | MAPTKMT2ATP53SMN1; SMN2GAA | |
| SCHEMBL9214221 | 0.81 | TDP1 (0.58) | PTGDR2MAPTRECQLTP53SMN1; SMN2 | |
| SCHEMBL11539949 | 0.81 | PKM (0.47) | PTGDR2PKMMEN1KMT2ARECQL | |
| SCHEMBL14419478 | 0.81 | PTGDR2 (0.57) | PTGDR2PKMMAPT | |
| SCHEMBL9912420 | 0.79 | FFAR1 (0.61) | PTGDR2PKMKDM4EFFAR1 | |
| SCHEMBL14066214 | 0.79 | PTGDR2 (0.60) | PTGDR2PKMSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |