Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274394 | 0.68 | KDM4E (0.36) | — | |
| Hydrochloric Acid SCHEMBL7277644 | 0.67 | KDM4E (0.36) | — | |
| SCHEMBL632166 | 0.65 | KDM4E (0.34) | — | |
| SCHEMBL9125147 | 0.64 | ALDH1A1 (0.41) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL6956307 | 0.64 | TBXAS1 (0.34) | HRH3HRH4 | |
| SCHEMBL30707445 | 0.63 | CHRM5 (0.50) | HRH3HRH4CHRM5MEN1LMNA | |
| SCHEMBL8176755 | 0.63 | TBXAS1 (0.36) | HRH3HRH4 | |
| SCHEMBL14334498 | 0.63 | DYRK1A (0.34) | LMNA | |
| SCHEMBL6958742 | 0.63 | TBXAS1 (0.36) | HRH3HRH4 | |
| SCHEMBL31200281 | 0.61 | CHRM5 (0.51) | CHRM5MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006037-A1 | NEW IMIDAZOLE DERIVATIVES HAVING AGONISTIC OR ANTAGONISTIC ACTIVITY ON THE HISTAMINE H3 RECEPTOR | VRIJE UNIVERSITEIT (NL) | 1995-03-02 | — | — | WO | disclosed |