Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201000 | 0.82 | GSK3B (0.41) | GSK3BMEN1KMT2AMAPTKDM4E | |
| SCHEMBL8098035 | 0.82 | GSK3B (0.41) | GSK3BMEN1KMT2AMAPTKDM4E | |
| SCHEMBL8094674 | 0.77 | CUL4A (0.43) | GSK3BMEN1KMT2AMAPTKDM4E | |
| SCHEMBL29137860 | 0.76 | GSK3B (0.41) | GSK3BMEN1KMT2AMAPTKDM4E | |
| SCHEMBL2483769 | 0.73 | CUL4A (0.47) | GSK3BMEN1KMT2AMAPTKDM4E | |
| SCHEMBL8745445 | 0.73 | MEN1 (0.36) | GSK3BMEN1KMT2AMAPTKDM4E | |
| SCHEMBL8376338 | 0.71 | KMT2A (0.59) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL9817948 | 0.69 | CES2 (0.43) | GSK3BMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9218012 | 0.69 | DAO (0.45) | GSK3B | |
| SCHEMBL8672684 | 0.69 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590458-B1 | Substituted thiophene carboxylic acid amides | BAYER AG (DE) | 1999-02-24 | — | — | EP | disclosed |
| EP-0755185-A1 | MICROBICIDAL AGENTS BASED ON DIBROMO-THIOPHENE-CARBOXYLIC ACID DERIVATIVES | BAYER AG (DE) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995027397-A1 | MICROBICIDAL AGENTS BASED ON DIBROMO-THIOPHENE-CARBOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-19 | — | — | WO | disclosed |
| EP-0450355-B1 | Compounds for the combat against plant diseases | DEGUSSA (DE) | 1995-08-09 | — | — | EP | disclosed |
| EP-0379003-B1 | Thiophene-2-carboxylic-acid derivatives, process for their preparation and their use in combating undesired plant growth | BASF AG (DE) | 1995-01-25 | — | — | EP | disclosed |
| EP-0590458-A1 | Substituted thiophene carboxylic acid amides | BAYER AG (DE) | 1994-04-06 | — | — | EP | disclosed |
| EP-0450355-A1 | Compounds for the combat against plant diseases | Degussa Aktiengesellschaft (DE) | 1991-10-09 | — | — | EP | disclosed |
| EP-0379003-A1 | Thiophene-2-carboxylic-acid derivatives, process for their preparation and their use in combating undesired plant growth | BASF Aktiengesellschaft (DE) | 1990-07-25 | — | — | EP | disclosed |