Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218134 | 1.00 | TSHR (0.42) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9220357 | 0.99 | TSHR (0.40) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9224883 | 0.89 | THRB (0.40) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9222880 | 0.87 | EPHX2 (0.33) | EPHX2DGKAHDAC8HDAC3HDAC1 | |
| SCHEMBL2608203 | 0.86 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9073493 | 0.86 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2608180 | 0.84 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29940900 | 0.84 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10427136 | 0.82 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9073332 | 0.81 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457172-A | An alkoxycarbonylalkylthio(or sulfone or sulfoxide) alkyl acrylate monomer; homo- and copolymers; molding materials; castings; binders; coating vehicles | ELF ATOCHEM S.A. (FR) | 1995-10-10 | — | — | US | claimed |