Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | HTR1D | P28221 | 3/20 | 0.40 |
| ▸ | HTR1B | P28222 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214509 | 0.91 | HTR1D (0.43) | SMN1; SMN2KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9218967 | 0.84 | HTR2A (0.44) | SMN1; SMN2KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9278907 | 0.81 | HTR1A (0.60) | SMN1; SMN2KDM4EMEN1KMT2AHTR1A | |
| SCHEMBL9210878 | 0.81 | HTR1A (0.38) | SMN1; SMN2MAPTMEN1KMT2AHTR1A | |
| SCHEMBL27439204 | 0.80 | MAPT (0.46) | SMN1; SMN2KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9218246 | 0.77 | HTR1A (0.69) | MAPTHTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL30181833 | 0.74 | KDM4E (0.49) | SMN1; SMN2KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9213440 | 0.69 | HTR2A (0.45) | SMN1; SMN2KDM4EMAPTHTR1DHTR1B | |
| SCHEMBL9214511 | 0.69 | HTR1D (0.73) | MAPTHTR1AHTR1DHTR1BGAA | |
| SCHEMBL9272892 | 0.68 | HTR1D (0.60) | KMT2AHTR1AHTR1DHTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995000478-A1 | ARYLTRIFLATES AND RELATED COMPOUNDS | LUNDBECK & CO AS H (DK) | 1995-01-05 | — | — | WO | disclosed |