Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 5/20 | 0.44 |
| ▸ | HTR1D | P28221 | 5/20 | 0.44 |
| ▸ | HTR1B | P28222 | 5/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9278907 | 0.87 | HTR1A (0.60) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL9214509 | 0.86 | HTR1D (0.43) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL9218239 | 0.84 | SMN1; SMN2 (0.47) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL9210878 | 0.82 | HTR1A (0.38) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL9218968 | 0.73 | HTR1D (0.77) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL9272892 | 0.73 | HTR1D (0.60) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL31134129 | 0.71 | HTR2A (0.50) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL15149020 | 0.69 | MTNR1A (0.42) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL4796985 | 0.68 | HTR2B (0.63) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL6063455 | 0.68 | HTR1A (0.56) | HTR2AHTR2CHTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995000478-A1 | ARYLTRIFLATES AND RELATED COMPOUNDS | LUNDBECK & CO AS H (DK) | 1995-01-05 | — | — | WO | disclosed |