Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218961 | 0.84 | KDM4E (0.47) | KMT2AMEN1HTTL3MBTL1KDM4E | |
| SCHEMBL9039039 | 0.82 | KMT2A (0.41) | KMT2AMEN1HTTL3MBTL1NCOA1 | |
| SCHEMBL27335609 | 0.71 | PABPC1 (0.50) | KMT2AMEN1HTTKDM4ELMNA | |
| SCHEMBL30437811 | 0.71 | MAPT (0.52) | KMT2AMEN1HTTL3MBTL1NCOA1 | |
| SCHEMBL9039042 | 0.67 | ALDH1A1 (0.47) | KMT2AMEN1HTTL3MBTL1NCOA1 | |
| SCHEMBL9077944 | 0.67 | ALDH1A1 (0.50) | KMT2AMEN1HTTKDM4ETDP1 | |
| SCHEMBL9079213 | 0.66 | FTO (0.46) | KMT2AMEN1HTTL3MBTL1KDM4E | |
| SCHEMBL28553829 | 0.66 | NQO2 (0.51) | KMT2AMEN1HTTL3MBTL1NCOA1 | |
| SCHEMBL9077993 | 0.66 | KDM4E (0.49) | HTTL3MBTL1KDM4ETDP1LMNA | |
| SCHEMBL9079040 | 0.66 | FTO (0.43) | KMT2AMEN1HTTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995000490-A1 | BIS-IMIDE POLYCYCLIC AND HETEROCYCLIC CHROMOPHORES USEFUL AS TUMORICIDALS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-01-05 | — | — | WO | disclosed |