Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 11/20 | 0.77 |
| ▸ | HTR1A | P08908 | 9/20 | 0.77 |
| ▸ | HTR1B | P28222 | 7/20 | 0.77 |
| ▸ | MPO | P05164 | 2/20 | 0.60 |
| ▸ | HTR6 | P50406 | 5/20 | 0.54 |
| ▸ | HTR2A | P28223 | 4/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | HTR1E | P28566 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | HTR5A | P47898 | 2/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HTR1F | P30939 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9278912 | 0.87 | HTR1D (1.00) | HTR1DHTR1AHTR1BMPOHTR6 | |
| SCHEMBL9214511 | 0.85 | HTR1D (0.73) | HTR1DHTR1AHTR1BMPOHTR6 | |
| SCHEMBL9218246 | 0.84 | HTR1A (0.69) | HTR1DHTR1AHTR1BMPOHTR6 | |
| SCHEMBL29400537 | 0.83 | HTR1A (1.00) | HTR1DHTR1AHTR1BMPOHTR6 | |
| SCHEMBL8892112 | 0.83 | HTR1A (1.00) | HTR1DHTR1AHTR1BMPOHTR6 | |
| SCHEMBL6063455 | 0.82 | HTR1A (0.56) | HTR1DHTR1AHTR1BHTR6HTR2A | |
| SCHEMBL9210881 | 0.82 | HTR1D (0.65) | HTR1DHTR1AHTR1BMPOHTR6 | |
| SCHEMBL23083090 | 0.81 | HTR1D (0.77) | HTR1DHTR1AHTR1BMPOHTR6 | |
| SCHEMBL30630375 | 0.81 | HTR1D (0.77) | HTR1DHTR1AHTR1BMPOHTR6 | |
| SCHEMBL27085184 | 0.80 | HTR1A (0.70) | HTR1DHTR1AHTR1BMPOHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995000478-A1 | ARYLTRIFLATES AND RELATED COMPOUNDS | LUNDBECK & CO AS H (DK) | 1995-01-05 | — | — | WO | disclosed |