Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 9/20 | 0.77 |
| ▸ | HTR1A | P08908 | 7/20 | 0.73 |
| ▸ | HTR1B | P28222 | 7/20 | 0.67 |
| ▸ | MPO | P05164 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.54 |
| ▸ | HTR3B | O95264 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR1E | P28566 | 1/20 | 0.54 |
| ▸ | HTR1F | P30939 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | HTR5A | P47898 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30630375 | 1.00 | HTR1D (0.77) | HTR1DHTR1AHTR1BMPOKMT2A | |
| SCHEMBL24243767 | 0.94 | HTR1D (0.72) | HTR1DHTR1AHTR1BCYP1A2CYP2D6 | |
| SCHEMBL23069144 | 0.91 | HTR1D (0.76) | HTR1DHTR1AHTR1BCYP1A2CYP2D6 | |
| SCHEMBL30630383 | 0.91 | HTR1D (0.76) | HTR1DHTR1AHTR1BCYP1A2CYP2D6 | |
| SCHEMBL27085158 | 0.90 | HTR1D (0.82) | HTR1DHTR1AHTR1BMPOKMT2A | |
| SCHEMBL27084869 | 0.90 | HTR1D (0.62) | HTR1DHTR1AHTR1BMPOHTR6 | |
| SCHEMBL23069149 | 0.90 | HTR1D (0.81) | HTR1DHTR1AHTR1BKMT2AHTR6 | |
| SCHEMBL30630353 | 0.90 | HTR1D (0.81) | HTR1DHTR1AHTR1BKMT2AHTR6 | |
| SCHEMBL27085175 | 0.90 | HTR1D (0.67) | HTR1DHTR1AHTR1BHTR6HTR2A | |
| SCHEMBL27085212 | 0.89 | HTR1D (0.79) | HTR1DHTR1AHTR1BMPOKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11911401-B2 | Tryptamine compositions for enhancing neurite outgrowth | TURTLE BEAR HOLDINGS, LLC (US) | 2024-02-27 | — | — | US | disclosed |
| US-20240043382-A1 | MODIFIED INDOLE ALKALOIDS FOR THERAPEUTIC USES | COMPASS PATHFINDER LIMITED (GB) | 2024-02-08 | — | — | US | disclosed |
| CN-117120415-A | Modified indole alkaloids for therapeutic use | 指南针探路者有限公司 | 2023-11-24 | — | — | CN | disclosed |
| US-20230210872-A1 | TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH | TURTLE BEAR HOLDINGS LLC (US) | 2023-07-06 | — | — | US | disclosed |
| US-11660305-B2 | Tryptamine compositions for enhancing neurite outgrowth | TURTLE BEAR HOLDINGS, LLC (US) | 2023-05-30 | — | — | US | disclosed |
| US-20210069170-A1 | TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH | TURTLE BEAR HOLDINGS, LLC | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11660305-B2 | Tryptamine compositions for enhancing neurite outgrowth | HTR1B, HTR6, BDNF | HTR1D 15/4885HTR1A 13/4885HTR1B 1/4885 |
| US-20240043382-A1 | MODIFIED INDOLE ALKALOIDS FOR THERAPEUTIC USES | INMT, AANAT, HNMT | HTR1D 664/4885HTR1A 181/4885HTR1B 324/4885 |
| US-20210069170-A1 | TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH | HTR1B, HTR6, BDNF | HTR1D 15/4885HTR1A 13/4885HTR1B 1/4885 |
| US-20230210872-A1 | TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH | HTR1B, HTR6, BDNF | HTR1D 15/4885HTR1A 13/4885HTR1B 1/4885 |
| US-11911401-B2 | Tryptamine compositions for enhancing neurite outgrowth | HTR1B, HTR6, BDNF | HTR1D 15/4885HTR1A 13/4885HTR1B 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.