Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219061 | 0.91 | MAPT (0.43) | MAPTALDH1A1HSD17B10MTNR1AMTNR1B | |
| SCHEMBL9215496 | 0.89 | ALDH1A1 (0.48) | MAPTALDH1A1HSD17B10MTNR1AMTNR1B | |
| SCHEMBL9220938 | 0.87 | MTNR1A (0.49) | MAPTMTNR1AMTNR1BKDM4EHPGD | |
| SCHEMBL9215491 | 0.82 | ALDH1A1 (0.44) | MAPTALDH1A1HSD17B10MTNR1AMTNR1B | |
| SCHEMBL9312321 | 0.81 | MAPT (0.42) | MAPTALDH1A1MTNR1AMTNR1BTP53 | |
| SCHEMBL9312641 | 0.79 | TBXAS1 (0.37) | MAPTMTNR1AMTNR1BKDM4EHPGD | |
| SCHEMBL9312539 | 0.79 | CHEK1 (0.37) | MAPTALDH1A1MTNR1AMTNR1BKDM4E | |
| SCHEMBL9313258 | 0.78 | FFAR1 (0.48) | SMN1; SMN2 | |
| SCHEMBL9220714 | 0.78 | MTNR1A (0.47) | MAPTALDH1A1MTNR1AMTNR1BKDM4E | |
| SCHEMBL9209256 | 0.77 | MTNR1A (0.48) | MAPTALDH1A1HSD17B10MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | claimed |
| US-5376677-A | Fungicides | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |