Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014346 | 0.85 | THRB (0.46) | THRBUSP2LMNAALDH1A1CYP1A2 | |
| SCHEMBL632454 | 0.84 | USP2 (0.42) | THRBUSP2LMNAALDH1A1TDP1 | |
| SCHEMBL19680485 | 0.84 | TDP1 (0.35) | THRBTDP1TSHR | |
| SCHEMBL4440314 | 0.83 | LMNA (0.40) | THRBUSP2LMNAALDH1A1TDP1 | |
| SCHEMBL5273525 | 0.81 | TDP1 (0.48) | THRBLMNATDP1TSHRMAPK1 | |
| SCHEMBL21177829 | 0.81 | USP2 (0.48) | USP2LMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL14321545 | 0.79 | USP2 (0.52) | USP2LMNACYP1A2KDM4EMEN1 | |
| SCHEMBL3902429 | 0.79 | TDP1 (0.38) | THRBUSP2LMNAALDH1A1TDP1 | |
| SCHEMBL3433696 | 0.79 | USP2 (0.41) | THRBUSP2LMNAALDH1A1TDP1 | |
| SCHEMBL3899149 | 0.79 | TDP1 (0.38) | THRBUSP2LMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995005154-A1 | CLEANSING COMPOSITION | UNILEVER PLC (GB) | 1995-02-23 | — | — | WO | disclosed |
| EP-0280579-B1 | LOW PHOSPHORUS/LOW ZINC LUBRICANTS | EXXON CHEMICAL PATENTS INC. (US) | 1992-11-11 | — | — | EP | disclosed |
| EP-0280579-A2 | Low phosphorus/low zinc lubricants | EXXON CHEMICAL PATENTS INC. (US) | 1988-08-31 | — | — | EP | disclosed |