SCHEMBL3433696

SCHEMBL3433696

CCC(C)OCC(O)CO

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.41
TDP1 Q9NUW8 2/20 0.38
LMNA P02545 4/20 0.36
ALDH1A1 P00352 1/20 0.36
KDM4E B2RXH2 2/20 0.36
DUSP3 P51452 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TSHR P16473 2/20 0.35
CYP1A2 P05177 2/20 0.33
AGTR1 P30556 1/20 0.33
MAPK1 P28482 1/20 0.32
DGKA P23743 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1829740 0.87 TDP1 (0.41) TDP1LMNAKDM4ETSHR
SCHEMBL12517107 0.85 TDP1 (0.40) TDP1KDM4ETSHR
SCHEMBL2353818 0.85 TDP1 (0.40) TDP1KDM4ETSHR
SCHEMBL4440314 0.85 LMNA (0.40) USP2TDP1LMNAALDH1A1KDM4E
SCHEMBL632454 0.82 USP2 (0.42) USP2TDP1LMNAALDH1A1KDM4E
SCHEMBL3902429 0.81 TDP1 (0.38) USP2TDP1LMNAALDH1A1KDM4E
SCHEMBL3899149 0.81 TDP1 (0.38) USP2TDP1LMNAALDH1A1KDM4E
SCHEMBL737250 0.81 TDP1 (0.38) USP2TDP1LMNAALDH1A1TSHR
SCHEMBL12091542 0.79 TSHR (0.39) TDP1LMNATSHR
SCHEMBL9219277 0.79 THRB (0.46) USP2TDP1LMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0066107-B1 2-HYDROXY-3-METHYL-BRANCHED-ALKOXYPROPYL GLYCERYL ETHER AND COSMETIC COMPOSITION CONTAINING SAME Kao Corporation (JP) 1985-08-14 EP claimed
US-11773266-B2 Polymer, molded body, foam, resin composition, and production method for polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-10-03 US disclosed
US-20230129965-A1 HYDROPHILIC AND OLEOPHOBIC POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-04-27 US disclosed
WO-2019142760-A1 HYALURONIDASE ACTIVITY INHIBITOR 株式会社ADEKA 2019-07-25 WO disclosed
CN-108367517-A Method for producing the haptic lens with lubricated surface 诺华股份有限公司 2018-08-03 CN disclosed
US-20180030175-A1 POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-01 US disclosed
US-8829229-B2 Polyol ethers and process for making them DOW GLOBAL TECHNOLOGIES LLC (US) 2014-09-09 US disclosed
US-8829229-B2 Polyol ethers and process for making them DOW GLOBAL TECHNOLOGIES LLC (US) 2014-09-09 US disclosed
EP-2318346-B1 POLYOL ETHERS AND PROCESS FOR MAKING THEM DOW GLOBAL TECHNOLOGIES LLC (US) 2013-11-20 EP disclosed
US-8329818-B2 Modified ethylene-vinyl alcohol copolymer and method for the production thereof KURARAY CO., LTD. (JP) 2012-12-11 US disclosed
WO-2010027663-A1 POLYOL ETHERS AND PROCESS FOR MAKING THEM DOW GLOBAL TECHNOLOGIES INC. (US) 2010-03-11 WO disclosed
US-20100048940-A1 reductive etherification of a polyol with an aldehyde or ketone using a hydrogenation catalyt; resulting compounds have use as solvents, surfactants, degreasers, wetting agents, emulsifying agents, lubricants, and intermediates for surfactants; polyols can be from renewable raw materials DOW GLOBAL TECHNOLOGIES LLC 2010-02-25 US disclosed
WO-2009115273-A1 NEW OXYGENATED COMPONENTS FOR FUELS AND PREPARATION THEREOF ENI S.P.A. (IT) 2009-09-24 WO disclosed
US-7534829-B2 Resin composition and multi-layer structures KURARAY CO., LTD. (JP) 2009-05-19 US disclosed
US-7365213-B2 Organosilicon compound, organosilicon resin having diol, and processes for producing these TOAGOSEI CO., LTD. (JP) 2008-04-29 US disclosed
US-6657089-B1 Reacting cyclic acetal containing hydroxy group with hydrogen in presence of palladium catalyst supported on mesoporous alumninosilicate; hydrogenation, decyclization, catalysis KAO CORPORATION (JP) 2003-12-02 US disclosed
EP-1236511-A1 PALLADIUM CATALYST AND PROCESS FOR PRODUCING ETHER Kao Corporation (JP) 2002-09-04 EP disclosed
EP-0624563-A1 Glycerin derivatives and process for producing the same KAO CORPORATION (JP) 1994-11-17 EP disclosed
EP-0080529-A1 2-Cyano-substituted 1,3-dioxane and dioxolane derivatives THE DOW CHEMICAL COMPANY (US) 1983-06-08 EP disclosed
US-4365073-A Derivatives of cyano-substituted ketones and aldehydes THE DOW CHEMICAL COMPANY (US) 1982-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048940-A1 reductive etherification of a polyol with an aldehyde or ketone using a hydrogenation catalyt; resulting compounds have use as solvents, surfactants, degreasers, wetting agents, emulsifying agents, lubricants, and intermediates for surfactants; polyols can be from renewable raw materials RNF114, USP14, USP13 USP2 70/4885TDP1 1846/4885LMNA 3728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.