Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 7/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9225461 | 1.00 | AVPR1A (0.47) | AVPR1AMAPK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9224938 | 0.87 | ACHE (0.43) | AVPR1A | |
| SCHEMBL9224944 | 0.87 | ACHE (0.43) | AVPR1A | |
| SCHEMBL9219422 | 0.84 | AVPR1A (0.35) | AVPR1ACYP3A4CYP2C19HSD11B1 | |
| SCHEMBL9219312 | 0.84 | AVPR1A (0.44) | AVPR1AMAPK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9219306 | 0.84 | AVPR1A (0.44) | AVPR1AMAPK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9225933 | 0.83 | AVPR1A (0.68) | AVPR1AMAPK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9225930 | 0.83 | AVPR1A (0.68) | AVPR1AMAPK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9227516 | 0.81 | HTR2A (0.37) | AVPR1ARAB9AALDH1A1 | |
| SCHEMBL9228503 | 0.78 | ALDH1A1 (0.42) | MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282895-B1 | 2-oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMA CO LTD (JP) | 1995-06-07 | — | — | EP | disclosed |
| US-5037976-A | Antimicrobial Agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| US-4898859-A | 2-Oxa-isocephem compounds and compositions containing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0282895-A2 | 2-oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |