Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 5/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9221279 | 0.84 | MCL1 (0.46) | MCL1MAOAMAOBALDH1A1KDM4E | |
| SCHEMBL10591223 | 0.83 | AHR (0.42) | MAOAMAOBKDM4EGAAMEN1 | |
| SCHEMBL10589478 | 0.81 | MCL1 (0.44) | MCL1MAOAMAOBALDH1A1KDM4E | |
| SCHEMBL15996310 | 0.81 | MAOA (0.47) | MCL1MAOAMAOBALDH1A1KDM4E | |
| SCHEMBL10590924 | 0.78 | KIF11 (0.47) | ALDH1A1PTGS2TDP1SMN1; SMN2 | |
| SCHEMBL3893100 | 0.78 | KDM4E (0.46) | MCL1MAOAMAOBALDH1A1KDM4E | |
| SCHEMBL9601061 | 0.77 | MCL1 (0.41) | MCL1MAOAMAOBALDH1A1KDM4E | |
| SCHEMBL28522401 | 0.77 | MAPK14 (0.54) | MAOAMAOBALDH1A1KDM4EGAA | |
| Bromide SCHEMBL29618239 | 0.77 | KDM4E (0.45) | MCL1MAOAMAOBALDH1A1KDM4E | |
| SCHEMBL7782881 | 0.76 | MAOA (0.51) | MCL1MAOAMAOBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347488-B1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID CO (US) | 1994-06-01 | — | — | EP | claimed |
| US-5010098-A | Arylpyrrole insecticidal acaricidal and nematicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-04-23 | — | — | US | claimed |
| EP-0347488-A1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-12-27 | — | — | EP | claimed |
| US-5455263-A | Administering substituted arylpyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1995-10-03 | — | — | US | disclosed |
| EP-0347488-B1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID CO (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5310938-A | Miticides, insecticides, parasiticides, and anthelmintics | AMERICAN CYANAMID COMPANY (US) | 1994-05-10 | — | — | US | disclosed |
| EP-0312723-B1 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID CO (US) | 1993-12-22 | — | — | EP | disclosed |
| US-5010098-A | Arylpyrrole insecticidal acaricidal and nematicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
| US-4929634-A | ARYLPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0358047-A2 | Method of controlling phytopathogenic fungi | AMERICAN CYANAMID COMPANY (US) | 1990-03-14 | — | — | EP | disclosed |
| EP-0347488-A1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-12-27 | — | — | EP | disclosed |
| EP-0312723-A2 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |