Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | RPA1 | P27694 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | DAO | P14920 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211471 | 0.73 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1HPGDCYP3A4CYP2C9 | |
| SCHEMBL1864417 | 0.73 | HCAR2 (0.35) | KMT2AMAPTKDM4E | |
| SCHEMBL3451427 | 0.71 | HCAR2 (0.49) | KMT2ALMNAMAPTKDM4E | |
| SCHEMBL9211802 | 0.71 | HCAR2 (0.34) | KMT2AMAPTKDM4E | |
| SCHEMBL9218638 | 0.69 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1HPGDKMT2AMEN1 | |
| SCHEMBL8803433 | 0.69 | HCAR2 (0.36) | — | |
| SCHEMBL9115479 | 0.68 | HCAR2 (0.55) | ALDH1A1L3MBTL1CYP3A4KMT2AMEN1 | |
| SCHEMBL9218976 | 0.67 | HCAR2 (0.38) | KMT2AMEN1LMNAHTTMAPT | |
| SCHEMBL4879037 | 0.64 | L3MBTL1 (0.33) | L3MBTL1KMT2AMAPTKDM4E | |
| SCHEMBL14822491 | 0.63 | KDM4E (0.45) | KMT2ADAOMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644879-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-03-29 | — | — | EP | disclosed |