Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 10/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.50 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219813 | 1.00 | AHCY (0.70) | AHCYADORA3ADORA1YTHDC1ADORA2A | |
| SCHEMBL15389856 | 0.92 | AHCY (0.71) | AHCYADORA3ADORA1YTHDC1ADORA2A | |
| SCHEMBL9212599 | 0.86 | AHCY (0.70) | AHCYADORA3ADORA1YTHDC1ADORA2A | |
| SCHEMBL9212609 | 0.86 | AHCY (0.70) | AHCYADORA3ADORA1YTHDC1ADORA2A | |
| Fluoro-Neplanocin A SCHEMBL9214735 | 0.82 | AHCY (1.00) | AHCYADORA3ADORA1ADORA2AADORA2B | |
| Fluoro-Neplanocin A SCHEMBL9215628 | 0.82 | AHCY (1.00) | AHCYADORA3ADORA1ADORA2AADORA2B | |
| Fluoro-Neplanocin A SCHEMBL9214745 | 0.82 | AHCY (1.00) | AHCYADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL15389855 | 0.81 | ADORA3 (0.53) | AHCYADORA3ADORA1YTHDC1ADORA2A | |
| SCHEMBL9221842 | 0.76 | AHCY (0.67) | AHCYADORA3ADORA1YTHDC1ADORA2A | |
| SCHEMBL9221846 | 0.76 | AHCY (0.67) | AHCYADORA3ADORA1YTHDC1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347852-B1 | Novel neplanocin derivatives | MERRELL DOW PHARMA (US) | 1995-08-23 | — | — | EP | disclosed |
| EP-0347852-A2 | Novel neplanocin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-12-27 | — | — | EP | disclosed |