Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 18/20 | 1.00 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.51 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.51 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.51 |
| ▸ | GAPDH | P04406 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | STAT6 | P42226 | 1/20 | 0.51 |
| ▸ | PI4KA | P42356 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.51 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.51 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoro-Neplanocin A SCHEMBL9215628 | 1.00 | AHCY (1.00) | AHCYADORA2BDPP4MEN1SLC28A1 | |
| Fluoro-Neplanocin A SCHEMBL9214735 | 1.00 | AHCY (1.00) | AHCYADORA2BDPP4MEN1SLC28A1 | |
| SCHEMBL15390405 | 0.92 | AHCY (1.00) | AHCYADORA2BDPP4ADORA3ADORA2A | |
| SCHEMBL863387 | 0.90 | AHCY (0.82) | AHCY | |
| SCHEMBL3793061 | 0.90 | AHCY (0.82) | AHCY | |
| SCHEMBL863521 | 0.90 | AHCY (1.00) | AHCY | |
| SCHEMBL1521121 | 0.90 | AHCY (0.82) | AHCY | |
| SCHEMBL10051881 | 0.89 | AHCY (0.84) | AHCY | |
| SCHEMBL9216846 | 0.85 | AHCY (1.00) | AHCYADORA2BDPP4MEN1SLC28A1 | |
| SCHEMBL9214869 | 0.85 | AHCY (1.00) | AHCYADORA2BDPP4MEN1SLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347852-B1 | Novel neplanocin derivatives | MERRELL DOW PHARMA (US) | 1995-08-23 | — | — | EP | claimed |
| EP-0347852-A2 | Novel neplanocin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-12-27 | — | — | EP | claimed |
| EP-2841109-B1 | PRODRUGS OF HYDROXYL-COMPRISING DRUGS | ASCENDIS PHARMA AS (DK) | 2026-04-15 | — | — | EP | disclosed |
| EP-3782649-B1 | BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS | ASCENDIS PHARMA AS (DK) | 2025-05-14 | — | — | EP | disclosed |
| US-20230381323-A1 | RELEASABLE CONJUGATES | FISH & RICHARDSON PC | 2023-11-30 | — | — | US | disclosed |
| US-11786599-B2 | Releasable conjugates | QUIAPEG PHARMACEUTICALS AB (SE) | 2023-10-17 | — | — | US | disclosed |
| US-20230123784-A1 | Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels | ASCENDIS PHARMA A/S (DK) | 2023-04-20 | — | — | US | disclosed |
| US-11559482-B2 | Biodegradable polyethylene glycol based water-insoluble hydrogels | ASCENDIS PHARMA A/S (DE) | 2023-01-24 | — | — | US | disclosed |
| EP-4011396-A1 | RELEASABLE CONJUGATES | QuiaPEG Pharmaceuticals AB (SE) | 2022-06-15 | — | — | EP | disclosed |
| US-9120760-B2 | Fluoro-homoneplanocin A and nucleoside derivatives, method for the synthesis thereof, and the pharmaceutical compositions comprising the same as an active component for treatment of cancer | EWHA University—Industry Collaboration Foundation (KR) | 2015-09-01 | — | — | US | disclosed |
| US-9120760-B2 | Fluoro-homoneplanocin A and nucleoside derivatives, method for the synthesis thereof, and the pharmaceutical compositions comprising the same as an active component for treatment of cancer | EWHA University—Industry Collaboration Foundation (KR) | 2015-09-01 | — | — | US | disclosed |
| US-20130310403-A1 | Fluoro-homoneplanocin A and nucleoside derivatives, method for the synthesis thereof, and the pharmaceutical compositions comprising the same as an active component for treatment of cancer | EWHA UNIVERSITY - INDUSTRY COLABORATION FOUNDATION (KR) | 2013-11-21 | — | — | US | disclosed |
| EP-0347852-B1 | Novel neplanocin derivatives | MERRELL DOW PHARMA (US) | 1995-08-23 | — | — | EP | disclosed |
| EP-0347852-A2 | Novel neplanocin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130310403-A1 | Fluoro-homoneplanocin A and nucleoside derivatives, method for the synthesis thereof, and the pharmaceutical compositions comprising the same as an active component for treatment of cancer | NME1, NTPCR, ENTPD5 | AHCY 828/4885ADORA2B 1666/4885DPP4 1005/4885 |
| US-20230123784-A1 | Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels | PLG, PHYKPL, PLOD3 | AHCY 412/4885ADORA2B 4314/4885DPP4 1529/4885 |
| US-20230381323-A1 | RELEASABLE CONJUGATES | GUSB, ABCB11, UGT2B7 | AHCY 1436/4885ADORA2B 228/4885DPP4 828/4885 |
| US-11559482-B2 | Biodegradable polyethylene glycol based water-insoluble hydrogels | PLG, PHYKPL, PLOD3 | AHCY 412/4885ADORA2B 4314/4885DPP4 1529/4885 |
| US-11786599-B2 | Releasable conjugates | GUSB, ABCB11, UGT2B7 | AHCY 1436/4885ADORA2B 228/4885DPP4 828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.