Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | XDH | P47989 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ULK1 | O75385 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23923776 | 0.74 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHSD17B10XDH | |
| SCHEMBL16240346 | 0.70 | LMNA (0.42) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL2404221 | 0.69 | CYP1A2 (0.36) | KDM4EALDH1A1HPGDHSD17B10XDH | |
| SCHEMBL10308264 | 0.69 | MAPK14 (0.49) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL3281275 | 0.68 | GAA (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL3146885 | 0.68 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL8203695 | 0.67 | NPSR1 (0.51) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL3579630 | 0.66 | FABP3 (0.42) | — | |
| SCHEMBL9219794 | 0.66 | MAPT (0.36) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL12021082 | 0.65 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409900-A | Treatment of cancer tumors, psoriasis; purification of blood | CYTOPHARM, INC. (US) | 1995-04-25 | — | — | US | disclosed |