Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16240346 | 0.83 | LMNA (0.42) | MAPTGAAMAPK1ALDH1A1HPGD | |
| SCHEMBL23923776 | 0.73 | ALDH1A1 (0.43) | MAPTGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL9454817 | 0.71 | ALDH1A1 (0.43) | MAPTGAAMAPK1ALDH1A1HPGD | |
| SCHEMBL11649989 | 0.69 | ALDH1A1 (0.51) | MAPTGAAMAPK1ALDH1A1HPGD | |
| SCHEMBL11646638 | 0.69 | CYP4F2 (0.48) | MAPTGAAMAPK1ALDH1A1HPGD | |
| SCHEMBL8203697 | 0.68 | HPGD (0.59) | MAPTMAPK1ALDH1A1HPGDKDM4E | |
| SCHEMBL3281275 | 0.67 | GAA (0.44) | MAPTGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL642906 | 0.67 | KDM4E (0.47) | MAPTGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL9219804 | 0.66 | KDM4E (0.37) | MAPTGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL5085234 | 0.65 | ALDH1A1 (0.46) | MAPTGAAMAPK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2808324-A1 | PYRROLE COMPOUND | Kabushiki Kaisha Yakult Honsha (JP) | 2014-12-03 | — | — | EP | disclosed |
| US-20140343017-A1 | PYRROLE COMPOUND | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2014-11-20 | — | — | US | disclosed |
| US-5409900-A | Treatment of cancer tumors, psoriasis; purification of blood | CYTOPHARM, INC. (US) | 1995-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343017-A1 | PYRROLE COMPOUND | TUBB3, TUBB1, TUBB | MAPT 214/4885GAA 4148/4885MAPK1 787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.