Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211748 | 0.92 | ADORA3 (0.49) | MCL1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL9220502 | 0.91 | MCL1 (0.51) | MCL1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL9210214 | 0.88 | MAPT (0.54) | MCL1KDM4EMEN1KMT2ACSNK2A2 | |
| SCHEMBL9218354 | 0.85 | ALDH1A1 (0.46) | MCL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9219801 | 0.84 | MCL1 (0.42) | MCL1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL9220326 | 0.82 | MAPT (0.54) | MCL1KDM4EMEN1KMT2ACSNK2A2 | |
| SCHEMBL9217470 | 0.79 | IP6K1 (0.42) | MCL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9212149 | 0.78 | SCN2A (0.50) | ALDH1A1NPC1RAB9AHPGDMAPT | |
| SCHEMBL9212333 | 0.77 | MAPT (0.46) | MCL1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL9431064 | 0.76 | MAPT (0.51) | MCL1KDM4EMEN1KMT2ACSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |