Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213625 | 0.96 | HPGD (0.46) | SCN2ASCN10ACNR1TP53ALDH1A1 | |
| SCHEMBL9218881 | 0.93 | SMN1; SMN2 (0.55) | SCN2ASCN10ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL9219766 | 0.91 | ALDH1A1 (0.53) | SCN2ASCN10ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL9216907 | 0.86 | ALDH1A1 (0.53) | SCN2ASCN10ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL9216807 | 0.85 | ALDH1A1 (0.52) | TP53ALDH1A1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL9221111 | 0.84 | ALDH1A1 (0.51) | TP53ALDH1A1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL9217404 | 0.83 | SMN1; SMN2 (0.60) | TP53ALDH1A1SMN1; SMN2CYP2C19MMP3 | |
| SCHEMBL9219589 | 0.82 | TP53 (0.45) | TP53ALDH1A1SMN1; SMN2LMNATHRB | |
| SCHEMBL9211345 | 0.81 | ALDH1A1 (0.48) | SCN2ASCN10ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL9218110 | 0.80 | ALDH1A1 (0.53) | TP53ALDH1A1SMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |