SCHEMBL9219916

SCHEMBL9219916

CCOP(C)(=O)CCC(N)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GCLC P48506 1/20 0.50
GLUL P15104 1/20 0.47
GRM8 O00222 2/20 0.46
GRM6 O15303 2/20 0.46
GRM4 Q14833 2/20 0.46
GRM7 Q14831 1/20 0.46
FOLH1 Q04609 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25703220 1.00 GCLC (0.50) GCLCGLULGRM8GRM6GRM4
Hydrochloric Acid SCHEMBL8459751 0.98 GCLC (0.49) GCLCGLULGRM8GRM6GRM4
SCHEMBL23660119 0.84 CYP2D6 (0.41) GCLCGLUL
SCHEMBL22216459 0.81 GLUL (0.50) GCLCGLULGRM8GRM6GRM4
SCHEMBL9219249 0.81 GLUL (0.44) GCLCGLULGRM8GRM6GRM4
SCHEMBL15160608 0.80 GABRR1 (0.41)
SCHEMBL28232738 0.79 GCLC (0.47) GCLCGLULGRM8GRM6GRM4
SCHEMBL9099903 0.79 GLUL (0.47) GCLCGLULGRM8GRM6GRM4
SCHEMBL2322125 0.77 PPARD (0.46) GCLCGLULGRM8GRM6GRM4
Glufosinate SCHEMBL28163644 0.77 GCLC (0.46) GCLCGLULGRM8GRM6GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170247399-A1 PROCESS OF PRODUCING PHOSPHINOTHRICIN EMPLOYING NITRILASES STRATEGIC ENZYME APPLICATIONS, INC. (US) 2017-08-31 US disclosed
US-9683001-B2 Process of producing phosphinothricin employing nitrilases Stragegic Enzyme Applications, Inc. (US) 2017-06-20 US disclosed
US-9683001-B2 Process of producing phosphinothricin employing nitrilases Stragegic Enzyme Applications, Inc. (US) 2017-06-20 US disclosed
US-20150239917-A1 Process of Producing Phosphinothricin Employing Nitrilases STRATEGIC ENZYME APPLICATIONS, INC. (US) 2015-08-27 US disclosed
US-8981142-B2 Process of producing phosphinothricin employing nitrilases STRATEGIC ENZYME APPLICATIONS, INC. (US) 2015-03-17 US disclosed
US-20130204031-A1 PROCESS OF PRODUCING PHOSPHINOTHRICIN EMPLOYING NITRILASES STRATEGIC ENZYME APPLICATIONS, INC. (US) 2013-08-08 US disclosed
EP-0358428-B1 Process for producing optically active compounds NISSAN CHEMICAL IND LTD (JP) 1995-04-26 EP disclosed
US-5081024-A Resolution by microbial fermentation NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1992-01-14 US disclosed
EP-0358428-A2 Process for producing optically active compounds NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1990-03-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170247399-A1 PROCESS OF PRODUCING PHOSPHINOTHRICIN EMPLOYING NITRILASES NPEPPS, NISCH, NAAA GCLC 1631/4885GLUL 378/4885GRM8 3829/4885
US-20150239917-A1 Process of Producing Phosphinothricin Employing Nitrilases NPEPPS, NISCH, NAAA GCLC 1631/4885GLUL 378/4885GRM8 3829/4885
US-20130204031-A1 PROCESS OF PRODUCING PHOSPHINOTHRICIN EMPLOYING NITRILASES NPEPPS, NISCH, NAAA GCLC 1631/4885GLUL 378/4885GRM8 3829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.