Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9221121 | 0.81 | PNMT (0.53) | PNMTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9228525 | 0.79 | ALDH1A1 (0.60) | RAB9ANPC1HPGDKMT2AMEN1 | |
| SCHEMBL9220147 | 0.77 | EPHX2 (0.59) | EPHX2RAB9ANPC1HPGDEPHX1 | |
| SCHEMBL3679238 | 0.76 | PNMT (0.42) | EPHX2RAB9ANPC1PNMTHPGD | |
| SCHEMBL9225866 | 0.76 | PNMT (0.50) | PNMTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL1568269 | 0.76 | PNMT (0.60) | RAB9ANPC1PNMTKMT2AMEN1 | |
| SCHEMBL225715 | 0.76 | PNMT (0.60) | RAB9ANPC1PNMT | |
| SCHEMBL11204188 | 0.75 | PNMT (0.63) | RAB9ANPC1PNMTHPGDKMT2A | |
| SCHEMBL21758216 | 0.75 | PNMT (0.58) | RAB9ANPC1PNMTKMT2AMEN1 | |
| SCHEMBL11570811 | 0.75 | PNMT (0.58) | RAB9ANPC1PNMTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420348-A | Enzyme inhibitors | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0447116-B1 | Urea derivatives, their production, and pharmaceutical compositions containing them | YAMANOUCHI PHARMA CO LTD (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5258405-A | Acetyl coenzyme A cholesterol acetyltransferase inhibitors for cardiovascular disorders and atherosclerosis and antilipemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1993-11-02 | — | — | US | disclosed |
| EP-0447116-A1 | Urea derivatives, their production, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-09-18 | — | — | EP | disclosed |