Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9224893 | 0.79 | HRH3 (0.51) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9220152 | 0.77 | EPHX2 (0.52) | EPHX2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL10089408 | 0.77 | EPHX2 (0.68) | EPHX2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL9227114 | 0.76 | SRD5A2 (0.58) | ALDH1A1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL3397254 | 0.76 | EPHX2 (1.00) | EPHX2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL5051924 | 0.76 | EPHX2 (1.00) | EPHX2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL2751293 | 0.75 | SIGMAR1 (0.68) | EPHX2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL4422952 | 0.75 | SRD5A2 (0.53) | ALDH1A1NPC1RAB9ALMNAHTT | |
| Methane SCHEMBL3680766 | 0.75 | SRD5A2 (0.57) | ALDH1A1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL27830632 | 0.74 | SRD5A2 (0.53) | ALDH1A1NPC1RAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420348-A | Enzyme inhibitors | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0447116-B1 | Urea derivatives, their production, and pharmaceutical compositions containing them | YAMANOUCHI PHARMA CO LTD (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5258405-A | Acetyl coenzyme A cholesterol acetyltransferase inhibitors for cardiovascular disorders and atherosclerosis and antilipemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1993-11-02 | — | — | US | disclosed |
| EP-0447116-A1 | Urea derivatives, their production, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-09-18 | — | — | EP | disclosed |