Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1156113 | 0.86 | JAK2 (0.52) | MDM2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL2658810 | 0.80 | TP53 (0.50) | TP53MDM2ALDH1A1KDM4EHPGD | |
| SCHEMBL15882405 | 0.78 | GCGR (0.57) | TP53MDM2ALDH1A1KDM4EHPGD | |
| SCHEMBL8665147 | 0.78 | TP53 (0.45) | TP53MDM2ALDH1A1KDM4EHPGD | |
| SCHEMBL8665022 | 0.77 | PRKCZ (0.52) | TP53MDM2ALDH1A1KDM4EHPGD | |
| SCHEMBL31029 | 0.77 | JAK2 (0.57) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL15497049 | 0.75 | TP53 (0.52) | TP53MDM2ALDH1A1KDM4EHPGD | |
| SCHEMBL1156930 | 0.75 | GABRA1 (0.50) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL15334465 | 0.74 | SMN1; SMN2 (0.49) | TP53MDM2ALDH1A1KDM4EHPGD | |
| SCHEMBL4949580 | 0.74 | SIRT2 (0.50) | TP53ALDH1A1KDM4EHPGDGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455263-A | Administering substituted arylpyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1995-10-03 | — | — | US | disclosed |
| US-5310938-A | Miticides, insecticides, parasiticides, and anthelmintics | AMERICAN CYANAMID COMPANY (US) | 1994-05-10 | — | — | US | disclosed |
| EP-0312723-B1 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID CO (US) | 1993-12-22 | — | — | EP | disclosed |
| US-5010098-A | Arylpyrrole insecticidal acaricidal and nematicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
| US-4929634-A | ARYLPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0358047-A2 | Method of controlling phytopathogenic fungi | AMERICAN CYANAMID COMPANY (US) | 1990-03-14 | — | — | EP | disclosed |
| EP-0347488-A1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-12-27 | — | — | EP | disclosed |
| EP-0312723-A2 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |