Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 13/20 | 0.55 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294995 | 0.94 | CTSS (0.56) | RENKLK5CTSSCTSLCTSB | |
| SCHEMBL16462611 | 0.93 | CTSS (0.57) | RENKLK5ATMKMT2ACTSS | |
| SCHEMBL16462608 | 0.93 | CTSS (0.57) | RENKLK5ATMKMT2ACTSS | |
| SCHEMBL27510152 | 0.89 | CTSS (0.53) | RENKLK5CTSSCTSLCTSB | |
| SCHEMBL27487264 | 0.89 | KLK5 (0.60) | RENKLK5CTSSCTSLCTSB | |
| SCHEMBL21269701 | 0.89 | KLK5 (0.60) | RENKLK5CTSSCTSLCTSB | |
| SCHEMBL30375069 | 0.89 | KLK5 (0.60) | RENKLK5CTSSCTSLCTSB | |
| SCHEMBL25492097 | 0.88 | REN (0.56) | RENKLK5KLK7 | |
| SCHEMBL9217713 | 0.87 | REN (0.50) | RENKLK5ATMKMT2ACTSS | |
| SCHEMBL30645045 | 0.87 | REN (0.55) | RENKLK5CTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |