SCHEMBL30645045

SCHEMBL30645045

COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)[C@H](C)NC(=O)OCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 8/20 0.55
▸ KLK5 Q9Y337 1/20 0.54
▸ CAPN1 P07384 2/20 0.54
▸ ALDH1A1 P00352 2/20 0.51
▸ THRB P10828 1/20 0.51
▸ CYP2C9 P11712 1/20 0.51
▸ CYP2C19 P33261 1/20 0.51
▸ HSD17B10 Q99714 1/20 0.51
▸ CTSK P43235 2/20 0.50
▸ CTSB P07858 2/20 0.50
▸ CTSL P07711 1/20 0.49
▸ ALOX15 P16050 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9223970 0.89 CTSK (0.56) RENCAPN1CTSKCTSBCTSL
SCHEMBL8441060 0.89 CTSL (0.55) CAPN1ALDH1A1CTSKCTSBCTSL
SCHEMBL18342569 0.88 CTSK (0.55) RENCAPN1CTSKCTSBCTSL
SCHEMBL20263594 0.88 CTSK (0.55) RENCAPN1CTSKCTSBCTSL
SCHEMBL10868800 0.88 CAPN1 (0.59) RENCAPN1ALDH1A1THRBCYP2C9
SCHEMBL10347011 0.88 CAPN1 (0.59) RENCAPN1ALDH1A1THRBCYP2C9
SCHEMBL1509254 0.88 CTSK (0.57) RENCAPN1CTSKCTSBCTSL
SCHEMBL11781682 0.87 ALDH1A1 (0.64) RENCAPN1ALDH1A1THRBCYP2C9
SCHEMBL9220259 0.87 REN (0.55) RENKLK5CTSKCTSBCTSL
SCHEMBL10432854 0.87 ITGB3 (0.56) CAPN1CTSKCTSBCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313594-A1 TWO-RESIDUE-EXTENDED PEPTIDE AND METHOD FOR PRODUCING SAME NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) 2025-10-09 — — US disclosed
EP-4527846-A1 TWO-RESIDUE-EXTENDED PEPTIDE AND METHOD FOR PRODUCING SAME NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) 2025-03-26 — — EP disclosed
WO-2023223714-A1 TWO-RESIDUE-EXTENDED PEPTIDE AND METHOD FOR PRODUCING SAME 国立大学法人東海国立大学機構 2023-11-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313594-A1 TWO-RESIDUE-EXTENDED PEPTIDE AND METHOD FOR PRODUCING SAME NPPA, NGLY1, ANPEP REN 464/4885KLK5 1696/4885CAPN1 2187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback