Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 5/20 | 0.44 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL262672 | 0.83 | CYP2C19 (0.47) | LMNAKIF11CYP2D6CYP2C19POLB | |
| SCHEMBL2060442 | 0.79 | LMNA (0.48) | LMNAKIF11CTBP2CYP3A4CYP2D6 | |
| Ethylamine SCHEMBL8958079 | 0.75 | LMNA (0.50) | LMNAKIF11CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1653535 | 0.74 | KIF11 (0.45) | LMNAKIF11CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2637169 | 0.73 | KIF11 (0.46) | LMNAKIF11CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8443853 | 0.73 | ACHE (0.50) | LMNAKIF11CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8185345 | 0.73 | PTPN5 (0.46) | LMNAKIF11CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4950628 | 0.73 | LMNA (0.47) | LMNAKIF11CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4941342 | 0.73 | LMNA (0.47) | LMNAKIF11CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1827125 | 0.73 | LMNA (0.47) | LMNAKIF11CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003044-A1 | BENZIMIDAZOLINONES SUBSTITUTED WITH PHENOXYPHENYLACETIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | disclosed |