SCHEMBL922210

SCHEMBL922210

Cc1ccc(C(=O)NCc2cccc(Oc3cccc(OC(F)(F)F)c3)c2)c(N)n1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARG P37231 12/20 0.58
PPARD Q03181 12/20 0.58
PPARA Q07869 12/20 0.58
MAPK14 Q16539 1/20 0.56
ROCK2 O75116 2/20 0.51
ROCK1 Q13464 2/20 0.51
KCNB1 Q14721 1/20 0.47
MMP13 P45452 1/20 0.47
GLS O94925 1/20 0.47
RIPK1 Q13546 1/20 0.46
CACNA1G O43497 1/20 0.46
CACNA1H O95180 1/20 0.46
CACNA1I Q9P0X4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921051 0.95 MAPK14 (0.58) PPARGPPARDPPARAMAPK14ROCK2
SCHEMBL921462 0.93 PPARD (0.53) PPARGPPARDPPARAMAPK14ROCK2
SCHEMBL922825 0.89 MAPK14 (0.57) PPARGPPARDPPARAMAPK14ROCK2
SCHEMBL920668 0.88 PPARG (0.56) PPARGPPARDPPARAMAPK14
SCHEMBL920306 0.88 HPGD (0.60) PPARGPPARDPPARAROCK2ROCK1
SCHEMBL920750 0.88 KDM4E (0.54) PPARGPPARDPPARAMAPK14MMP13
SCHEMBL920003 0.87 PPARG (0.57) PPARGPPARDPPARAMAPK14MMP13
SCHEMBL919651 0.87 MAPT (0.50) PPARGPPARDPPARAROCK2ROCK1
SCHEMBL919789 0.87 PPARG (0.53) PPARGPPARDPPARAMAPK14ROCK2
SCHEMBL922174 0.87 KDM4E (0.53) PPARGPPARDPPARAROCK2ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 PPARG 391/4885PPARD 360/4885PPARA 494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.