SCHEMBL922174

SCHEMBL922174

Cc1cccc(Oc2cccc(CNC(=O)c3ccc(C)nc3N)c2)c1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.53
ALDH1A1 P00352 2/20 0.53
HPGD P15428 2/20 0.53
HSD17B10 Q99714 1/20 0.53
PPARG P37231 7/20 0.50
PPARD Q03181 7/20 0.50
PPARA Q07869 7/20 0.50
USP2 O75604 1/20 0.50
MMP13 P45452 3/20 0.48
CHRM4 P08173 1/20 0.48
ROCK2 O75116 1/20 0.46
ROCK1 Q13464 1/20 0.46
ADORA2A P29274 2/20 0.45
ADORA1 P30542 1/20 0.44
APEX1 P27695 1/20 0.44
LMNA P02545 1/20 0.44
TP53 P04637 1/20 0.44
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921580 0.93 MMP13 (0.58) KDM4EALDH1A1HPGDHSD17B10PPARG
SCHEMBL920420 0.93 MAPK14 (0.49) KDM4EALDH1A1HPGDHSD17B10PPARG
SCHEMBL920750 0.92 KDM4E (0.54) KDM4EALDH1A1HPGDHSD17B10PPARG
SCHEMBL920306 0.90 HPGD (0.60) KDM4EALDH1A1HPGDPPARGPPARD
SCHEMBL920504 0.89 KDM4E (0.51) KDM4EALDH1A1HPGDHSD17B10PPARG
SCHEMBL920712 0.89 KMT2A (0.53) KDM4EALDH1A1HPGDPPARGPPARD
SCHEMBL920568 0.89 MMP13 (0.57) KDM4EALDH1A1HPGDPPARGPPARD
SCHEMBL922070 0.89 HPGD (0.51) KDM4EALDH1A1HPGDHSD17B10PPARG
SCHEMBL919977 0.89 HPGD (0.48) KDM4EALDH1A1HPGDHSD17B10PPARG
SCHEMBL919651 0.89 MAPT (0.50) KDM4EALDH1A1HPGDPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101951771-A Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens SUMITOMO CHEMICAL CO 2011-01-19 CN disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 KDM4E 3657/4885ALDH1A1 2743/4885HPGD 1273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.