SCHEMBL922255

SCHEMBL922255

Cc1cc(-c2ccc(C)c(O)c2C)cc(C)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
ALDH1A1 P00352 2/20 0.44
CYP1A2 P05177 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
ELANE P08246 2/20 0.37
FYN P06241 2/20 0.37
ALOX5 P09917 4/20 0.36
PTGS1 P23219 3/20 0.36
PTGS2 P35354 3/20 0.36
G6PD P11413 2/20 0.36
ESR2 Q92731 2/20 0.36
GAA P10253 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TTR P02766 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31547671 0.83 POLB (0.48) CA1CA2ALDH1A1CYP1A2CYP2C9
SCHEMBL920891 0.83 POLB (0.48) CA1CA2ALDH1A1CYP1A2CYP2C9
SCHEMBL5526665 0.83 CA1 (0.52) CA1CA2ALDH1A1CYP1A2CYP2C9
SCHEMBL1513737 0.80 ESR2 (0.53) CA1CA2ALDH1A1ELANEALOX5
SCHEMBL7106703 0.80 ALDH1A1 (0.42) CA1CA2ALDH1A1ELANEALOX5
SCHEMBL8895164 0.80 CA1 (0.54) CA1CA2ALDH1A1CYP1A2CYP2C9
SCHEMBL3752346 0.79 CA1 (0.59) CA1CA2ALDH1A1CYP1A2CYP2C9
SCHEMBL9571457 0.79 CA1 (0.59) CA1CA2ALDH1A1CYP1A2CYP2C9
SCHEMBL28356274 0.78 HSD17B1 (0.49) ALDH1A1CYP1A2CYP2C9CYP2C19ESR2
Propane SCHEMBL10606493 0.76 POLB (0.42) ALDH1A1CYP1A2CYP2C9CYP2C19ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481238-B2 Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2013-07-09 US disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-7985522-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-26 US disclosed
EP-1770447-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY MITSUBISHI CHEM CORP (JP) 2011-03-16 EP disclosed
US-20110013934-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2011-01-20 US disclosed
US-20100183332-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTORS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-07-22 US disclosed
EP-2154575-A2 Electrophotographic photoreceptor Mitsubishi Chemical Corporation (JP) 2010-02-17 EP disclosed
US-7604913-B2 Electrophotographic photosensitive body MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-20 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090047589-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-19 US disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 US disclosed
EP-1770447-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Mitsubishi Chemical Corporation (JP) 2007-04-04 EP disclosed